Filippo Graziani

Periodontitis and diabetes. Preventive and therapeutic implications of a well-studied association

  • Full Professor of Periodontology of the University of Pisa (Italy)
  • He is responsible of the Unit of “Periodontology, Halitosis and Periodontal Medicine” of the University Hospital of Pisa
  • At the present is also Visiting Professor in Periodontology at UCL of London (Eastman Institute) and Honorary Professor at the Faculty of Dentistry, Hong Kong
  • His clinical activities are fully dedicated to Periodontology and e runs his private practice limited to periodontology
  • He obtained his DDS in Pisa and then a PhD in Oral and Maxillo-Facial Surgery
  • He gained the Mastership in Periodontology at the Eastman Dental Institute of London
  • He also holds a Master in Clinical research and an Oral Surgery Specialty
  • He has been elected as President of the European Federation of Periodontology in 2019
  • He is the coordinator of the European Day of Periodontology 2017 and chairman of the European Project Committee of the European Federation of Periodontology
  • His research activities focus on periodontal surgical treatment and periodontal medicine
  • He published more than 70 scientific manuscripts in impacted factor journals
  • Reviewer of numerous scientific journals, associate Editor of Minerva Stomatologica and member of the Editorial Board of the Journal of Clinical Periodontology
  • He was awarded in 2013 with Earl Robinson Award for Periodontal Regeneration of the American Academy of Periodontology, in 2015 with the Clinical research -Jaccard Prize of the European Federation of Periodontology and in 2017 the Goldman prize of the Italian Society of Periodontology and Implantology
  • He won numerous research grants from institutional and private companies to run his research activities

Nationality: Italy

Scientific areas: Oral health | General health

14 of november, from 14h30 until 15h15

Auditório B

Conference summary

In the last two decades there has been a real explosion in research into possible associations between periodontitis and systemic diseases and conditions. The best current evidence suggests that periodontitis is characterized by both infection and pro-inflammatory events, which variously manifest within certain systemic disorders. Two mechanisms have been postulated to play an important role in non-oral manifestations of oral diseases: dissemination of bacteria or of their toxins and production of inflammatory mediators having an impact on systemic inflammation mediated by innate immune cells and mediators. This relationship between periodontitis and systemic health is not linear but quite complex.

Nowadays, there is consistent and strong epidemiologic evidence that periodontitis imparts increased risk for future cardiovascular disease. Robust evidence has emerged that severe periodontitis adversely affects glycaemic control in diabetes and glycaemia in non-diabetes subjects. Furthermore, in diabetes patients there is a direct and dose-dependent relationship between periodontitis severity and diabetes complications.

It is then of uttermost importance to take notice on the possible effects of periodontal treatment on the glycemic status. Indeed treatment of periodontitis in subjects affected by diabetes is associate by an improvement of glycated hemoglobins level and free blood glucose level. It is therefore crucial that dentists and physicians recognize the critical role of periodontal treatment in the overall management of patients with diabetes.

 

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